(-)-camphene synthase

(-)-camphene synthase (EC 4.2.3.117, CS) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase (cyclizing, (-)-camphene-forming).^[1]^[2]^[3]^[4] This enzyme catalyses the following chemical reaction

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(-)-Camphene is the major product in Abies grandis (grand fir) with traces of other monoterpenoids.

References

↑ Bohlmann, J.; Phillips, M.; Ramachandiran, V.; Katoh, S.; Croteau, R. (1999). "cDNA cloning, characterization, and functional expression of four new monoterpene synthase members of the Tpsd gene family from grand fir (Abies grandis)". Arch. Biochem. Biophys. 368: 232–243. doi:10.1006/abbi.1999.1332. PMID 10441373.
↑ Huber, D.P.W.; Philippe, R.N.; Godard, K.-A.; Sturrock, R.N.; Bohlmann, J. (2005). "Characterization of four terpene synthase cDNAs from methyl jasmonate-induced Douglas-fir, Pseudotsuga menziesii". Phytochemistry. 66: 1427–1439. doi:10.1016/j.phytochem.2005.04.030. PMID 15921711.
↑ Hyatt, D.C.; Croteau, R. (2005). "Mutational analysis of a monoterpene synthase reaction: altered catalysis through directed mutagenesis of (-)-pinene synthase from Abies grandis". Arch. Biochem. Biophys. 439: 222–233. doi:10.1016/j.abb.2005.05.017. PMID 15978541.
↑ Falara, V.; Akhtar, T.A.; Nguyen, T.T.; Spyropoulou, E.A.; Bleeker, P.M.; Schauvinhold, I.; Matsuba, Y.; Bonini, M.E.; Schilmiller, A.L.; Last, R.L.; Schuurink, R.C.; Pichersky, E. (2011). "The tomato terpene synthase gene family". Plant Physiol. 157 (2): 770–789. doi:10.1104/pp.111.179648. PMID 21813655.

(-)-camphene synthase at the US National Library of Medicine Medical Subject Headings (MeSH)

Carbon-oxygen lyases (EC 4.2) (primarily dehydratases)

4.2.1: Hydro-Lyases	Carbonic anhydrase Fumarase Aconitase Enolase Alpha Enolase 2 Enoyl-CoA hydratase/3-Hydroxyacyl ACP dehydrase Methylglutaconyl-CoA hydratase Tryptophan synthase Cystathionine beta synthase Porphobilinogen synthase 3-Isopropylmalate dehydratase Urocanase Uroporphyrinogen III synthase Nitrile hydratase

4.2.2: Acting on polysaccharides	Hyaluronate lyase

4.2.3: Acting on phosphates	Threonine synthase

4.2.99: Other	Carboxymethyloxysuccinate lyase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list)

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