(R)-Perdesonide
Ball and stick structure of (R)-isomer of perdesonide | |
Identifiers | |
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CAS Number | 83603-33-2 |
Chemical and physical data | |
Formula | C25H32F2O6 |
Molar mass | 466.52 g·mol−1 |
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(R)-Perdesonide is one of the two isomers of perdesonide, a glucocorticoid steroid. There is a dioxolane moiety with a chiral carbon at position 3; this was introduced to reduce mineralocorticoid activity. The (R)-isomer of the acetal has been shown to be the most potent in this class of steroid. Perdesonide resembles clocortolone in that both have two halide atoms; perdesonide has two fluorine atoms and clocortolone has one chlorine atom and one fluorine atom.[1]
See also
References
- ↑ “Foye's Principles of Medicinal Chemistry”
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