4,4'-Methylenebis(2-chloroaniline)
Names | |
---|---|
IUPAC name
4-[(4-Amino-3-chlorophenyl)methyl]-2-chloroaniline | |
Other names
•4,4'-Methylene-bis(2-chloroaniline) •Cyanaset •Quodorole •Dacpm •Curalin M •Diamet Kh •Millionate M •Bis amine •MOCA •Bisamine S | |
Identifiers | |
101-14-4 | |
3D model (Jmol) | Interactive image |
ChEMBL | ChEMBL82846 |
ChemSpider | 7262 |
ECHA InfoCard | 100.002.654 |
KEGG | C10999 |
PubChem | 7543 |
UNII | 3L2W5VTT2A |
| |
| |
Properties | |
C13H12Cl2N2 | |
Molar mass | 267.15 g·mol−1 |
Appearance | Tan-colored pellets or flakes[1] |
Odor | faint, amine-like[1] |
Density | 1.44 g/cm3[1] |
Melting point | 104 to 109 °C (219 to 228 °F; 377 to 382 K)[2] |
insoluble | |
Vapor pressure | 0.00001 mmHg (20°C)[1] |
Hazards | |
Main hazards | potential occupational carcinogen[1] |
NFPA 704 | |
Flash point | 203 °C (397 °F; 476 K) |
US health exposure limits (NIOSH): | |
PEL (Permissible) |
none[1] |
REL (Recommended) |
Ca TWA 0.003 mg/m3 [skin][1] |
IDLH (Immediate danger) |
Ca [N.D.][1] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
verify (what is ?) | |
Infobox references | |
4,4'-Methylenebis(2-chloroaniline) (MOCA, MBOCA, bisamine) is a substance used as a curing agent in polyurethane production.[3] It is a proven human carcinogen standing on the WHO List of IARC Group 1 carcinogens, with a current threshold limit value of 0.01 ppm in the industrial atmosphere. Animal studies have resulted in tumor growth in the liver, lung, and bladder.[1] Employee exposure is often monitored by measurement of urinary MOCA in free and/or conjugated form.[4]
It is a weak base with a slight odor and is reactive to active metals such as sodium, potassium, magnesium and zinc.[1]
References
- 1 2 3 4 5 6 7 8 9 10 "NIOSH Pocket Guide to Chemical Hazards #0411". National Institute for Occupational Safety and Health (NIOSH).
- ↑ "4,4'-Methylenebis(2-chloroaniline)". TCI Chemicals. Retrieved March 17, 2014.
- ↑ RTK HSFS 1250
- ↑ 4,4'-Methylene bis (2-chloroaniline) Health Guideline, Occupational Safety and Health Administration
This article is issued from Wikipedia - version of the 11/15/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.