ATP5S

ATP5S
Identifiers
Aliases	ATP5S, ATPW, FB, HSU79253, ATP synthase, H+ transporting, mitochondrial Fo complex subunit s (factor B)
External IDs	MGI: 1915305 HomoloGene: 12232 GeneCards: ATP5S
Gene ontology Molecular function • hydrogen ion transmembrane transporter activity • metal ion binding Cellular component • mitochondrion • membrane • proton-transporting ATP synthase complex, coupling factor F(o) • mitochondrial inner membrane Biological process • mitochondrial ATP synthesis coupled proton transport • ion transport • transport • proton transport • ATP biosynthetic process Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	27109	68055
Ensembl	ENSG00000125375	ENSMUSG00000054894
UniProt	Q99766	Q9CRA7
RefSeq (mRNA)	NM_001003803 NM_001003805 NM_015684	NM_026536
RefSeq (protein)	NP_001003803.1 NP_001003805.1 NP_056499.2	NP_080812.1
Location (UCSC)	Chr 14: 50.31 – 50.34 Mb	Chr 12: 69.72 – 69.74 Mb
PubMed search	[1]	[2]
Wikidata

ATP synthase subunit s, mitochondrial is an enzyme that in humans is encoded by the ATP5S gene.^[3][4][5]

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. This gene encodes the subunit s, also known as factor B, of the proton channel. This subunit is necessary for the energy transduction activity of the ATP synthase complexes. Alternatively spliced transcript variants encoding different isoforms have been identified.^[5]

References

Further reading