Acetarsol

Acetarsol
Names
Preferred IUPAC name
Acetarsone
Systematic IUPAC name
(3-Acetamido-4-hydroxyphenyl)arsonic acid[1]
Other names
3-Acetamido-4-hydroxyphenylarsonic acid
Identifiers
97-44-9 N
3D model (Jmol) Interactive image
Interactive image
ChEMBL ChEMBL1330792 N
ChemSpider 1908 YesY
ECHA InfoCard 100.002.349
EC Number 202-582-3
KEGG D07110 YesY
MeSH Acetarsol
PubChem 1985
UNII 806529YU1N YesY
UN number 3465
Properties
C8H10AsNO5
Molar mass 275.0903 g mol−1
Pharmacology
A07AX02 (WHO) G01AB01 (WHO), P01CD02 (WHO), P51AD05 (WHO)
Hazards
GHS pictograms
GHS signal word Danger
H301, H331, H410
P261, P273, P301+310, P311, P501
T N
R-phrases R23/25, R50/53
S-phrases S20/21, S28, S45, S60, S61
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Acetarsol is an anti-infective.[2]

It was first discovered in 1921 at Pasteur Institute by Ernest Fourneau, and sold under the brand name Stovarsol (fourneau is the French word for stove).[3][4]

It has been given in suppositories.[5]

Acetarsol can be used to make Arsthinol, & presumably Acetarsone also.

References

  1. ↑ "acetarsol - PubChem Public Chemical Database". The PubChem Project. USA: National Center for Biotechnology Information.
  2. ↑ Chen MY, Smith NA, Fox EF, Bingham JS, Barlow D (April 1999). "Acetarsol pessaries in the treatment of metronidazole resistant Trichomonas vaginalis". Int J STD AIDS. 10 (4): 277–80. doi:10.1258/0956462991913943. PMID 12035784.
  3. ↑ Éric Fouassier, Ces poisons qui guérissent, oct. 1996, p. 5.
  4. ↑ Traité de chimie organique, sous la direction de Victor Grignard, Paul Baud, vol. 22, Masson, 1959, p. 1127-1130.
  5. ↑ Gionchetti P, Rizzello F, Morselli C, Campieri M (October 2004). "Review article: problematic proctitis and distal colitis". Aliment. Pharmacol. Ther. 20 Suppl 4: 93–6. doi:10.1111/j.1365-2036.2004.02049.x. PMID 15352902.
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