Altoqualine
 | |
| Names | |
|---|---|
| IUPAC name
(3S)-7-Amino-4,5,6-triethoxy-3-[(1R)-6,7,8-trimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]-3H-2-benzofuran-1-one | |
| Other names
458 L | |
| Identifiers | |
| 121029-11-6 | |
| 3D model (Jmol) | Interactive image |
| ChEMBL | ChEMBL2104645 |
| ChemSpider | 2301104 |
| PubChem | 3037346 |
| |
| |
| Properties | |
| C27H36N2O8 | |
| Molar mass | 516.59 g·mol−1 |
| Melting point | 144 °C (291 °F; 417 K)[1] |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Altoqualine is an isoquinoline once studied for its potential use as an antihistamine and antiallergic,[1][2][3] but it was never a marketed drug. It is an inhibitor of histidine decarboxylase.[2]
References
- 1 2 C.R. Ganellin; David J. Triggle (Nov 21, 1996). Dictionary of Pharmacological Agents,. 1–2. CRC Press. p. 58.
- 1 2 Lallouette P, Mordelet-Dambrine M, Treize G, N'Guyen VT, Dubois AM, Parrot JL (1981). "Pharmacological approach of a new isoquinoline derivative (458 L)". Agents and actions. 11 (1–2): 41–43. doi:10.1007/BF01991453. PMID 7195643.
- ↑ Bargnoux H, Kantelip JP, Bastide M, Duchene-Marullaz P, Boyer R, Lallouette P, Petit J, Berger JA (1990). "Pharmacokinetic study of a new benzyl-1 isoquinoline derivative (458 L) after oral administration in men". Therapie. 45 (1): 7–11. PMID 1971461.
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