Anti-smooth muscle antibody

Anti-smooth muscle antibodies are antibodies (immunoglobulins) formed against smooth muscle. These antibodies are typically associated with autoimmune hepatitis.^[1]^[2]

These antibodies can be directed against actin, troponin, and tropomyosin.^[3]

References

↑ Dawkins, RL; Joske RA (June 1973). "Immunoglobulin deposition in liver of patients with active chronic hepatitis and antibody against smooth muscle". British Medical Journal. 2 (5867): 643–645. doi:10.1136/bmj.2.5867.643. PMC 1589647. PMID 4577016.
↑ M. Eric Gershwin (2007). Liver immunology: principles and practice. Humana Press. pp. 265–. ISBN 978-1-58829-818-8. Retrieved 26 October 2010.
↑ Kenneth Michael Pollard (2006). Autoantibodies and autoimmunity: molecular mechanisms in health and disease. Wiley-VCH. pp. 293–. ISBN 978-3-527-31141-5. Retrieved 26 October 2010.

Medical test: Antibodies: autoantibodies

Anti-nuclear antibody	PBC: Anti-gp210 Anti-p62 Anti-sp100 ENA: Anti-topoisomerase/Scl-70 Anti-Jo1 ENA4 Anti-Sm Anti-nRNP Anti-Ro Anti-La Anti-centromere Anti-dsDNA

Anti-mitochondrial antibody	Anti-cardiolipin

Anti-cytoplasm antibody	Anti-neutrophil cytoplasmic C-ANCA P-ANCA Anti-smooth muscle Anti-actin Anti-TPO/Antimicrosomal

Cell membrane	Anti-ganglioside Anti-GBM Anti-glutamate

Extracellular	Anti-thrombin Lupus anticoagulant Coeliac disease: Anti-transglutaminase Anti-gliadin not autoantibody RA Rheumatoid factor/anti-IgG Anti-citrullinated peptide

Multiple locations	Anti-phospholipid Anti-apolipoprotein

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