Lipid A acylase

Antimicrobial peptide resistance and lipid A acylation protein PagP

Identifiers

Symbol

PagP

268

Available protein structures:
Pfam	structures
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Antimicrobial peptide resistance and lipid A acylation protein PagP is a family of several bacterial antimicrobial peptide resistance and lipid A acylation (PagP) proteins. The bacterial outer membrane enzyme PagP transfers a palmitate chain from a phospholipid to lipid A. In a number of pathogenic Gram-negative bacteria, PagP confers resistance to certain cationic antimicrobial peptides produced during the host innate immune response.

References

Hwang, P. M.; Choy, W. Y.; Lo, E. I.; Chen, L.; Forman-Kay, J. D.; Raetz, C. R.; Privé, G. G.; Bishop, R. E.; Kay, L. E. (2002). "Solution structure and dynamics of the outer membrane enzyme PagP by NMR". Proceedings of the National Academy of Sciences. 99 (21): 13560–13565. doi:10.1073/pnas.212344499. PMC 129713. PMID 12357033.

This article is issued from Wikipedia - version of the 8/27/2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.