Butynamine

Butynamine
Clinical data


ATC code	none
Identifiers
IUPAC name N-tert-Butyl-N,2-dimethylbut-3-yn-2-amine
CAS Number	3735-65-7
PubChem (CID)	189910
ChemSpider	164936
UNII	313QE5199Z^Y
ChEMBL	CHEMBL2104389
Chemical and physical data
Formula	C₁₀H₁₉N
Molar mass	153.26 g/mol
3D model (Jmol)	Interactive image
SMILES CC(C)(C)N(C)C(C)(C)C#C
InChI InChI=1S/C10H19N/c1-8-10(5,6)11(7)9(2,3)4/h1H,2-7H3 Key:PAVORIOUUILGMQ-UHFFFAOYSA-N

Butynamine is a tertiary (a highly hindered) aliphatic amine which has antihypertensive effects.^[1]

References

↑ BREST AN, ONESTI G, SWARTZ C, BERLINER H, MOYER JH (June 1962). "Butynamine hydrochloride as an antihypertensive agent". Current Therapeutic Research, Clinical and Experimental. 4: 313–6. PMID 13872883.

Central

α₂ agonist	Clonidine Guanabenz Guanfacine Methyldopa^# Tiamenidine^‡

Adrenergic release inhibitors	Bethanidine Bretylium Debrisoquine Guanadrel Guanazodine Guanethidine Guanoclor Guanazodine Guanoxabenz Guanoxan

Imidazoline receptor agonist	Moxonidine Rilmenidine Tolonidine

Ganglion-blocking/nicotinic antagonist	Hexamethonium^‡ Mecamylamine Pentolinium Trimethaphan

Peripheral

Indirect

MAOI	Pargyline^‡

Adrenergic uptake inhibitor	Bietaserpine Deserpidine Methoserpidine Rescinnamine Reserpine

Tyrosine hydroxylase inhibitor	Metirosine

Direct

α₁ blockers	Prazosin Indoramin Trimazosin Doxazosin Urapidil

Non-selective α blocker	Phentolamine

Serotonin antagonist	Ketanserin Lidanserin

Endothelin antagonist (for PH)	dual (Bosentan, Macitentan) selective (Ambrisentan, Sitaxentan)

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