CLDN15

CLDN15

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
4P79

Identifiers

External IDs

MGI: 1913103 HomoloGene: 8646 GeneCards: CLDN15

Gene ontology
Molecular function	• structural molecule activity • identical protein binding
Cellular component	• integral component of membrane • cell junction • plasma membrane • lateral plasma membrane • membrane • bicellular tight junction
Biological process	• calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules • ion transport • transport
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


24146


60363


ENSG00000106404


ENSMUSG00000001739


P56746


Q9Z0S5

RefSeq (mRNA)


NM_138429 NM_001185080 NM_014343


NM_021719

RefSeq (protein)


NP_001172009.1 NP_055158.1


NP_068365.1

Location (UCSC)

Chr 7: 101.23 – 101.24 Mb

Chr 5: 136.97 – 136.98 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

Claudin-15 is a protein that in humans is encoded by the CLDN15 gene.^[3] It belongs to the group of claudins.

References

Further reading

Kniesel U, Wolburg H (2000). "Tight junctions of the blood–brain barrier.". Cell. Mol. Neurobiol. 20 (1): 57–76. doi:10.1023/A:1006995910836. PMID 10690502.
Heiskala M, Peterson PA, Yang Y (2001). "The roles of claudin superfamily proteins in paracellular transport.". Traffic. 2 (2): 93–8. doi:10.1034/j.1600-0854.2001.020203.x. PMID 11247307.
Tsukita S, Furuse M, Itoh M (2001). "Multifunctional strands in tight junctions.". Nat. Rev. Mol. Cell Biol. 2 (4): 285–93. doi:10.1038/35067088. PMID 11283726.
Tsukita S, Furuse M (2003). "Claudin-based barrier in simple and stratified cellular sheets.". Curr. Opin. Cell Biol. 14 (5): 531–6. doi:10.1016/S0955-0674(02)00362-9. PMID 12231346.
González-Mariscal L, Betanzos A, Nava P, Jaramillo BE (2003). "Tight junction proteins.". Prog. Biophys. Mol. Biol. 81 (1): 1–44. doi:10.1016/S0079-6107(02)00037-8. PMID 12475568.
Yi X, Wang Y, Yu FS (2000). "Corneal epithelial tight junctions and their response to lipopolysaccharide challenge.". Invest. Ophthalmol. Vis. Sci. 41 (13): 4093–100. PMID 11095601.
Kiuchi-Saishin Y, Gotoh S, Furuse M, et al. (2002). "Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments.". J. Am. Soc. Nephrol. 13 (4): 875–86. PMID 11912246.
Colegio OR, Van Itallie CM, McCrea HJ, et al. (2002). "Claudins create charge-selective channels in the paracellular pathway between epithelial cells.". Am. J. Physiol., Cell Physiol. 283 (1): C142–7. doi:10.1152/ajpcell.00038.2002. PMID 12055082.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Van Itallie CM, Fanning AS, Anderson JM (2003). "Reversal of charge selectivity in cation or anion-selective epithelial lines by expression of different claudins.". Am. J. Physiol. Renal Physiol. 285 (6): F1078–84. doi:10.1152/ajprenal.00116.2003. PMID 13129853.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Liu F, Koval M, Ranganathan S, Fanayan S, Hancock WS, Lundberg EK, Beavis RC, Lane L, Duek P, McQuade L, Kelleher NL, Baker MS (2015). "A systems proteomics view of the endogenous human claudin protein family". J Proteome Res. doi:10.1021/acs.jproteome.5b00769. PMID 26680015.

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