CLDN20

CLDN20

Available structures

Human UniProt search: PDBe RCSB

List of PDB id codes
4YYX

Identifiers

External IDs

MGI: 3646757 HomoloGene: 47972 GeneCards: CLDN20

Gene ontology
Molecular function	• structural molecule activity • identical protein binding
Cellular component	• integral component of membrane • cell junction • plasma membrane • membrane • bicellular tight junction
Biological process	• calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


49861


621628


ENSG00000171217


ENSMUSG00000091530


P56880


n/a

RefSeq (mRNA)


NM_001001346


NM_001101560

RefSeq (protein)


NP_001001346.1


n/a

Location (UCSC)

Chr 6: 155.26 – 155.28 Mb

Chr 17: 3.53 – 3.53 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

Claudin-20 is a protein that in humans is encoded by the CLDN20 gene.^[3]^[4] It belongs to the group of claudins.

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Hewitt KJ, Agarwal R, Morin PJ (Aug 2006). "The claudin gene family: expression in normal and neoplastic tissues". BMC Cancer. 6: 186. doi:10.1186/1471-2407-6-186. PMC 1538620. PMID 16836752.
↑ "Entrez Gene: CLDN20 claudin 20".

Further reading

Kniesel U, Wolburg H (2000). "Tight junctions of the blood–brain barrier". Cell. Mol. Neurobiol. 20 (1): 57–76. doi:10.1023/A:1006995910836. PMID 10690502.
Heiskala M, Peterson PA, Yang Y (2001). "The roles of claudin superfamily proteins in paracellular transport". Traffic. 2 (2): 93–8. doi:10.1034/j.1600-0854.2001.020203.x. PMID 11247307.
Tsukita S, Furuse M, Itoh M (2001). "Multifunctional strands in tight junctions". Nat. Rev. Mol. Cell Biol. 2 (4): 285–93. doi:10.1038/35067088. PMID 11283726.
Tsukita S, Furuse M (2003). "Claudin-based barrier in simple and stratified cellular sheets". Curr. Opin. Cell Biol. 14 (5): 531–6. doi:10.1016/S0955-0674(02)00362-9. PMID 12231346.
González-Mariscal L, Betanzos A, Nava P, Jaramillo BE (2003). "Tight junction proteins". Prog. Biophys. Mol. Biol. 81 (1): 1–44. doi:10.1016/S0079-6107(02)00037-8. PMID 12475568.
Berg M, Geisel A, Necheles H (1975). "The influence of carbenoxolone on steroid-induced ulcer and mucus secretion in the rat". The American journal of digestive diseases. 20 (2): 134–7. doi:10.1007/BF01072339. PMID 1124737.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Liu F, Koval M, Ranganathan S, Fanayan S, Hancock WS, Lundberg EK, Beavis RC, Lane L, Duek P, McQuade L, Kelleher NL, Baker MS (2015). "A systems proteomics view of the endogenous human claudin protein family". J Proteome Res. doi:10.1021/acs.jproteome.5b00769. PMID 26680015.

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