Adenozil-chloride synthase

Adenosyl-chloride synthase (EC 2.5.1.94, chlorinase, 5'-chloro-5'-deoxyadenosine synthase) is an enzyme with systematic name S-adenosyl-L-methionine:chloride adenosyltransferase.^[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + chloride

\rightleftharpoons

5-deoxy-5-chloroadenosine + L-methionine

This enzyme is isolated from the marine bacterium Salinispora tropica.

References

↑ Eustaquio, A.S.; Pojer, F.; Noel, J.P.; Moore, B.S. (2008). "Discovery and characterization of a marine bacterial SAM-dependent chlorinase". Nat. Chem. Biol. 4 (1): 69–74. doi:10.1038/nchembio.2007.56. PMC 2762381. PMID 18059261.

External links

Adenosyl-chloride synthase at the US National Library of Medicine Medical Subject Headings (MeSH)

Transferases: alkyl and aryl (EC 2.5)

2.5.1	Dimethylallyltranstransferase Thiaminase I Methionine adenosyltransferase Riboflavin synthase Dihydropteroate synthase Spermidine synthase Glutathione S-transferase Farnesyl-diphosphate farnesyltransferase Spermine synthase Alkylglycerone phosphate synthase Farnesyltransferase Geranylgeranyltransferase type 1 Porphobilinogen deaminase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list)

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