Cocksfoot mottle virus
| Cocksfoot mottle virus (CoMV) | |
|---|---|
| Virus classification | |
| Group: | Group IV ((+)ssRNA) |
| Order: | Unassigned |
| Family: | Unassigned |
| Genus: | Sobemovirus |
| Species: | Cocksfoot mottle virus |
| Synonyms | |
| |
Cocksfoot mottle virus (CfMV) is a pathogenic plant virus belonging to the genus Sobemovirus. The virus appears in southern and central England. It is transmitted by beetles Lema melanopa and Lema lichenis and is common in crops of cocksfoot and cocksfoot/legume mixtures.[1]
Molecular biology
CfMV's P1 protein, required for infection, has been found to interfere with RNAi pathways in plants species such as Nicotiana benthamiana and Nicotiana tabacum.[2]
The polyprotein coat of CfMV is made up of two proteins, encoded by overlapping open reading frames (2a and 2b) which are transcribed through a ribosomal frameshift mechanism.[3] This mechanism is reliant upon a small stem-loop structure and a 'slippery' repeat sequence which allows programmed ribosomal frameshifting.[4]
References
- ↑ http://www.dpvweb.net/dpv/showdpv.php?dpvno=23
- ↑ Cecilia Sarmiento; Eva Gomez; Merike Meier; Tony A Kavanagh & Erkki Truve (January 2007). "Cocksfoot mottle virus P1 suppresses RNA silencing in Nicotiana benthamiana and Nicotiana tabacum". Virus research. 123 (1): 95–99. doi:10.1016/j.virusres.2006.07.013. PMID 16971015.
- ↑ Mäkinen K, Mäkeläinen K, Arshava N, et al. (November 2000). "Characterization of VPg and the polyprotein processing of cocksfoot mottle virus (genus Sobemovirus)". J. Gen. Virol. 81 (Pt 11): 2783–9. PMID 11038392. Retrieved 2011-07-08.
- ↑ Tamm T, Suurväli J, Lucchesi J, Olspert A, Truve E (December 2009). "Stem-loop structure of Cocksfoot mottle virus RNA is indispensable for programmed -1 ribosomal frameshifting". Virus Res. 146 (1-2): 73–80. doi:10.1016/j.virusres.2009.09.002. PMID 19748532. Retrieved 2011-07-08.