DDX6

DDX6
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases DDX6, HLR2, P54, RCK, DEAD-box helicase 6
External IDs MGI: 104976 HomoloGene: 3238 GeneCards: DDX6
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

1656

13209

Ensembl

ENSG00000110367

ENSMUSG00000032097

UniProt

P26196

P54823

RefSeq (mRNA)

NM_001257191
NM_004397

NM_001110826
NM_007841
NM_181324

RefSeq (protein)

NP_001244120.1
NP_004388.2

NP_001104296.1
NP_031867.1
NP_851841.2

Location (UCSC) Chr 11: 118.75 – 118.79 Mb Chr 9: 44.6 – 44.64 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Probable ATP-dependent RNA helicase DDX6 is an enzyme that in humans is encoded by the DDX6 gene.[3][4]

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein. It may contribute to the cell proliferation and carcinogenesis.[4]

References

Further reading


This article is issued from Wikipedia - version of the 6/29/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.