Delphinium denudatum

Delphinium denudatum
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
Order: Ranunculales
Family: Ranunculaceae
Genus: Delphinium
Species: D. denudatum
Binomial name
Delphinium denudatum
Wall

Delphinium denudatum is a species of the genus Delphinium.

Habitat

Delphinium denudatum is found on the outer ranges of western Himalayas from Kashmir to Kumaon at a height between 8000 to 12000 feet above sea level.

Medicinal properties

It is one of the important drugs used as indigenous medicine in India, especially in Unani medicine.[1][2] Its vernacular name is Jadwar.

The roots of the plant are reported to be useful in a variety of ailments such as aconite poisoning, brain diseases, fungal infection, piles and toothache as analgesic and astringent.[3][4][5] A number of studies have been done on its phytochemical and pharmacological properties.[6][7]

Its use in opium addiction is mentioned in some classical literature,[8][9] which has been verified and validated in morphine-induced physical dependent de-addiction studies.[10][11][12][13][14][15][16][17][18][19]

References

  1. ↑ Nizami, Qudsia; Jafri, MA (2006). "Unani drug, Jadwar (Delphinium denudatum Wall.) - A review". Indian Journal of Traditional Knowledge. 5 (4): 463–467.
  2. ↑ Zafar S, Aftab MA, Siddiqui TA. Jadwar (Delphinium denudatum Wall.) Roots – A Boon in Unani Medicine, Hamdard Medicus, Vol. XLVI, No. 2, 2003: 9-14
  3. ↑ Baytar Ibn. Jame al Mufradat al advia wal aghzia. Cairo: Bulak Press; 1874: 159
  4. ↑ Khory RN, Katrak NN. Materia Medica of India and their therapeutics. Delhi: Neeraj Publishing House; 1985: 10–11
  5. ↑ Rahman A, Nasreen A, Akhtar F, Shekhani MS, Clardy J, Parvez M, Choudhary MI. Antifungal diterpenoid alkaloids from Delphinium denudatum. J Nat Prod. 1997;60:472–4
  6. ↑ Singh N, Singh A, Malik MS. Delphinium denudatum alkaloid, the structure of denudatine. Chem Ind. 1961: 1909-11
  7. ↑ Singh N, Chopra KL. Diterpine alkaloid isolation and study of two new alkaloids. J Pharma and Pharmaceutic. 1962;14:288–93
  8. ↑ Khan Najmul Ghani. Qarabadin-i Najmul Ghani (Urdu). 2nd ed. Lucknow: Naval Kishore Press; 1928: 621
  9. ↑ Shirazi IM. Treatise on Opium. A 16th Century Persian manuscript Aligarh: Zillur Rahman Library, Ibn Sina Academy of Medieval Medicine & Sciences; Scribed between 1737 and 1744. p. 28.
  10. ↑ Rahman, SZ (Syed Ziaur Rahman); Khan, RA; Kumar, A (May 2002). "Experimental study of the morphine de-addiction properties of Delphinium denudatum Wall.". BMC Complement Altern Med. 2 (6): 6. doi:10.1186/1472-6882-2-6. PMC 116424Freely accessible. PMID 12036433.
  11. ↑ Chase, Christina (June 2003). "Study shows Delphinium denudatum aids in de-addiction of morphine (Review)". HerbClip, American Botanical Council, Austin, TX, USA: HC#010133–234.
  12. ↑ Rahman, SZ; Khan, RA; Kumar, A (December 2003). "CNS depressant effect of delphinium denudatum wall. with special reference to its role in morphine addiction". Journal of Neurochemistry. 87 (Suppl. 1): 68–68. doi:10.1046/j.1474-1644.2003.2175_4.x. ISI:000187240200233 IDS Number: 753PR.
  13. ↑ Rahman, SZ; Khan, RA; Kumar, A (February 2004). "Delphinium denudatum Wall and its CNS activities particularly in morphine addiction". Journal of Neurochemistry. 88 (Suppl. 1): 34–34. doi:10.1046/j.1474-1644.2003.2314p8_01.x. ISI:000189078700103 IDS Number: 775UH.
  14. ↑ Rahman, SZ; Khan, RA; Kumar, A (August 2004). "Delphinium denudatum Wall and its CNS depressant effect particularly in morphine addiction". Journal of Neurochemistry. 90 (Suppl. 1): 145–145. doi:10.1111/j.1471-4159.2004.02693P.x. ISI:000223760900456 IDS Number: 852NB.
  15. ↑ Rahman, SZ; Khan, RA; Kumar, A (August 2005). "Pharmacological studies of an indigenous CNS-active drug delphinium denudatum wall. in view of its role in morphine addiction". Journal of Neurochemistry. 94 (Suppl. 2): 95–95. doi:10.1111/j.1474-1644.2005.03323.x. ISI:000231673400258 IDS Number: 961PD.
  16. ↑ Rahman, SZ; Khan, RA; Kumar, A (August 2007). "Pharmacological study of delphinium denudatum wall. in morphine de-addiction.". Journal of Neurochemistry. 102 (Suppl. 1): 142–143. doi:10.1111/j.0022-3042.2007.04727.x. ISI:000248991600345 IDS Number: 203RL.
  17. ↑ Rahman, S. Z., Khan R. A. & Kumar A. A Study of Delphinium denudatum Wall. in morphine dependence. In: Khan SS, editor. Vistas in Ethnobotany, Ind J Applied Pure Biol. Vol. 1. 2000: 111–125
  18. ↑ Rahman, S. Z., Khan R.A & Kumar A. Preclinical study of delphinium denudatum wall. in morphine de-addiction. Journal of Pharmacological and Toxicological Methods September–October 2007, Volume 56 (2): e4
  19. ↑ Rahman, S. Z., Khan, R. A & Kumar, A. A Study of Delphinium denudatum in moderately induced morphine dependence, Proceedings, 6th Internet World Congress for Biomedical Sciences, Castilla La Mancha University, Spain, February 14–25, 2000
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