Prednicarbate

Prednicarbate
Clinical data
AHFS/Drugs.com Monograph
MedlinePlus a604021
Routes of
administration
Topical
ATC code D07AC18 (WHO)
Identifiers
Synonyms [2-[(8S,9S,10R,11S,13S,14S,17R)-17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate
CAS Number 73771-04-7 YesY
PubChem (CID) 6714002
IUPHAR/BPS 7605
DrugBank DB01130 N
ChemSpider 5145991 N
UNII V901LV1K7D N
ChEMBL CHEMBL1200386 N
ECHA InfoCard 100.070.516
Chemical and physical data
Formula C27H36O8
Molar mass 488.57 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Prednicarbate is a relatively new topical corticosteroid drug. It is similar in potency to hydrocortisone. Compared to other topical corticosteroids, like betamethasone, repeated prednicarbate use does not cause skin atrophy as quickly. Corticosteroids have always been an important part of the pharmacological arsenal of dermatology; however, their tendency to produce side-effects has caused the need to search for new preparations.

It is nonhalogenated.[1]

References

  1. Gupta AK, Chow M (2004). "A review of prednicarbate (Dermatop)". Skin Therapy Lett. 9 (10): 5–6, 9. PMID 15657633.


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