FKBP9

Identifiers

FKBP9, FKBP60, FKBP63, PPIase, FK506 binding protein 9

External IDs

Gene ontology
Molecular function	• calcium ion binding • FK506 binding • isomerase activity • peptidyl-prolyl cis-trans isomerase activity • metal ion binding
Cellular component	• endoplasmic reticulum • endoplasmic reticulum membrane
Biological process	• protein folding • chaperone-mediated protein folding • protein peptidyl-prolyl isomerization
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


11328


27055


ENSG00000122642


ENSMUSG00000029781


O95302


Q9Z247

RefSeq (mRNA)


NM_001284341 NM_001284343 NM_007270


NM_012056

RefSeq (protein)


NP_001271270.1 NP_001271272.1 NP_009201.2


NP_036186.2

Location (UCSC)

PubMed search

^[1]

^[2]

FK506-binding protein 9 is a protein that in humans is encoded by the FKBP9 gene.^[3]^[4]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Patterson CE, Gao J, Rooney AP, Davis EC (May 2002). "Genomic organization of mouse and human 65 kDa FK506-binding protein genes and evolution of the FKBP multigene family". Genomics. 79 (6): 881–9. doi:10.1006/geno.2002.6777. PMID 12036304.
↑ "Entrez Gene: FKBP9 FK506 binding protein 9, 63 kDa".

Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Zhang H, Li XJ, Martin DB, Aebersold R (2003). "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.". Nat. Biotechnol. 21 (6): 660–6. doi:10.1038/nbt827. PMID 12754519.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Shadidy M, Caubit X, Olsen R, et al. (1999). "Biochemical analysis of mouse FKBP60, a novel member of the FKPB family.". Biochim. Biophys. Acta. 1446 (3): 295–307. doi:10.1016/s0167-4781(99)00080-9. PMID 10524204.

Isomerases: geometric (EC 5.2)

5.2.1	FKBP: FKBP1A FKBP1B FKBP2 FKBP3 FKBP5 FKBP6 FKBP8 FKBP9 FKBP10 FKBP52 FKBPL other: Cyclophilin Parvulin Prolyl isomerase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list)

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