Glutathione amide reductase
| Glutathione amide reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.8.1.16 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Glutathione amide reductase (EC 1.8.1.16, GAR) is an enzyme with systematic name glutathione amide:NAD+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction
- 2 glutathione amide + NAD+ glutathione amide disulfide + NADH + H+
Glutathione amide reductase is a dimeric flavoprotein (FAD).
References
- ↑ Vergauwen, B.; Pauwels, F.; Jacquemotte, F.; Meyer, T.E.; Cusanovich, M.A.; Bartsch, R.G.; Van Beeumen, J.J. (2001). "Characterization of glutathione amide reductase from Chromatium gracile. Identification of a novel thiol peroxidase (Prx/Grx) fueled by glutathione amide redox cycling". J. Biol. Chem. 276: 20890–20897. doi:10.1074/jbc.M102026200. PMID 11399772.
- ↑ Vergauwen, B.; Van Petegem, F.; Remaut, H.; Pauwels, F.; Van Beeumen, J.J. (2002). "Crystallization and preliminary X-ray crystallographic analysis of glutathione amide reductase from Chromatium gracile". Acta Crystallogr. D. 58 (Pt 2): 339–340. doi:10.1107/s0907444901020303. PMID 11807270.
External links
- Glutathione amide reductase at the US National Library of Medicine Medical Subject Headings (MeSH)
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