Glycoside hydrolase family 32
| Glycosyl hydrolases family 32 N-terminal domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 beta-fructosidase from thermotoga maritima in complex with raffinose | |||||||||
| Identifiers | |||||||||
| Symbol | Glyco_hydro_32N | ||||||||
| Pfam | PF00251 | ||||||||
| Pfam clan | CL0143 | ||||||||
| InterPro | IPR013148 | ||||||||
| PROSITE | PDOC00532 | ||||||||
| CAZy | GH32 | ||||||||
| |||||||||
| Glycosyl hydrolases family 32 C terminal | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 crystal structure of exo-inulinase from aspergillus awamori in spacegroup p21 | |||||||||
| Identifiers | |||||||||
| Symbol | Glyco_hydro_32C | ||||||||
| Pfam | PF08244 | ||||||||
| InterPro | IPR013189 | ||||||||
| PROSITE | PDOC00532 | ||||||||
| CAZy | GH32 | ||||||||
| |||||||||
In molecular biology, glycoside hydrolase family 32 is a family of glycoside hydrolases.
Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.[1][2][3] This classification is available on the CAZy(http://www.cazy.org/GH1.html) web site,[4] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.[5]
Family 32 glycosyl hydrolases comprise two distinct domains. The N-terminal domain, which forms a five bladed beta propeller, and the C-terminal domain, which forms a beta sandwich structure.[6]
References
- ↑ Henrissat B, Callebaut I, Mornon JP, Fabrega S, Lehn P, Davies G (1995). "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proc. Natl. Acad. Sci. U.S.A. 92 (15): 7090–7094. doi:10.1073/pnas.92.15.7090. PMC 41477
. PMID 7624375. - ↑ Henrissat B, Davies G (1995). "Structures and mechanisms of glycosyl hydrolases". Structure. 3 (9): 853–859. doi:10.1016/S0969-2126(01)00220-9. PMID 8535779.
- ↑ Bairoch, A. "Classification of glycosyl hydrolase families and index of glycosyl hydrolase entries in SWISS-PROT". 1999.
- ↑ Henrissat, B. and Coutinho P.M. "Carbohydrate-Active Enzymes server". 1999.
- ↑ CAZypedia, an online encyclopedia of carbohydrate-active enzymes.
- ↑ Alberto F, Bignon C, Sulzenbacher G, Henrissat B, Czjzek M (2004). "The three-dimensional structure of invertase (beta-fructosidase) from Thermotoga maritima reveals a bimodular arrangement and an evolutionary relationship between retaining and inverting glycosidases.". J Biol Chem. 279 (18): 18903–10. doi:10.1074/jbc.M313911200. PMID 14973124.
This article incorporates text from the public domain Pfam and InterPro IPR013189
This article incorporates text from the public domain Pfam and InterPro IPR013148