Glycoside hydrolase family 46
Glyco_hydro_46 | |||||||||
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streptomyces n174 chitosanase ph5.5 298k | |||||||||
Identifiers | |||||||||
Symbol | Glyco_hydro_46 | ||||||||
Pfam | PF01374 | ||||||||
Pfam clan | CL0037 | ||||||||
InterPro | IPR000400 | ||||||||
SCOP | 1chk | ||||||||
SUPERFAMILY | 1chk | ||||||||
CAZy | GH46 | ||||||||
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In molecular biology, glycoside hydrolase family 46 is a family of glycoside hydrolases.
Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.[1][2][3] This classification is available on the CAZy(http://www.cazy.org/GH1.html) web site,[4] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.[5]
Glycoside hydrolase family 46 CAZY GH_46 comprises enzymes with only one known activity; chitosanase (EC 3.2.1.132). Chitosanase enzymes catalyse the endohydrolysis of beta-1,4-linkages between N-acetyl-D-glucosamine and D-glucosamine residues in a partly acetylated chitosan.
References
- ↑ Henrissat B, Callebaut I, Mornon JP, Fabrega S, Lehn P, Davies G (1995). "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proc. Natl. Acad. Sci. U.S.A. 92 (15): 7090–7094. doi:10.1073/pnas.92.15.7090. PMC 41477. PMID 7624375.
- ↑ Henrissat B, Davies G (1995). "Structures and mechanisms of glycosyl hydrolases". Structure. 3 (9): 853–859. doi:10.1016/S0969-2126(01)00220-9. PMID 8535779.
- ↑ Bairoch, A. "Classification of glycosyl hydrolase families and index of glycosyl hydrolase entries in SWISS-PROT". 1999.
- ↑ Henrissat, B. and Coutinho P.M. "Carbohydrate-Active Enzymes server". 1999.
- ↑ CAZypedia, an online encyclopedia of carbohydrate-active enzymes.
This article incorporates text from the public domain Pfam and InterPro IPR000400