Glycoside hydrolase family 53
| Glycosyl hydrolase family 53 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 crystal structure of beta-1,4-galactanase from aspergillus aculeatus at 100k | |||||||||
| Identifiers | |||||||||
| Symbol | Glyco_hydro_53 | ||||||||
| Pfam | PF07745 | ||||||||
| Pfam clan | CL0058 | ||||||||
| InterPro | IPR011683 | ||||||||
| SCOP | 1fob | ||||||||
| SUPERFAMILY | 1fob | ||||||||
| OPM superfamily | 125 | ||||||||
| OPM protein | 1hjq | ||||||||
| CAZy | GH53 | ||||||||
| |||||||||
In molecular biology, glycoside hydrolase family 53 is a family of glycoside hydrolases.
Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.[1][2][3] This classification is available on the CAZy(http://www.cazy.org/GH1.html) web site,[4] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.[5]
These enzymes are endo-1,4- beta-galactanases EC 3.2.1.89. The structure of this domain is known [6] and has a TIM barrel fold.
References
- ↑ Henrissat B, Callebaut I, Mornon JP, Fabrega S, Lehn P, Davies G (1995). "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proc. Natl. Acad. Sci. U.S.A. 92 (15): 7090–7094. doi:10.1073/pnas.92.15.7090. PMC 41477
. PMID 7624375. - ↑ Henrissat B, Davies G (1995). "Structures and mechanisms of glycosyl hydrolases". Structure. 3 (9): 853–859. doi:10.1016/S0969-2126(01)00220-9. PMID 8535779.
- ↑ Bairoch, A. "Classification of glycosyl hydrolase families and index of glycosyl hydrolase entries in SWISS-PROT". 1999.
- ↑ Henrissat, B. and Coutinho P.M. "Carbohydrate-Active Enzymes server". 1999.
- ↑ CAZypedia, an online encyclopedia of carbohydrate-active enzymes.
- ↑ Ryttersgaard C, Lo Leggio L, Coutinho PM, Henrissat B, Larsen S (December 2002). "Aspergillus aculeatus beta-1,4-galactanase: substrate recognition and relations to other glycoside hydrolases in clan GH-A". Biochemistry. 41 (51): 15135–43. doi:10.1021/bi026238c. PMID 12484750.
This article incorporates text from the public domain Pfam and InterPro IPR011683