Insect pheromone-binding protein
| Insect pheromone-binding family, A10/OS-D | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 antennal chemosensory protein a6 from the moth mamestra brassicae | |||||||||
| Identifiers | |||||||||
| Symbol | OS-D | ||||||||
| Pfam | PF03392 | ||||||||
| InterPro | IPR005055 | ||||||||
| SCOP | 1n8v | ||||||||
| SUPERFAMILY | 1n8v | ||||||||
| OPM superfamily | 377 | ||||||||
| OPM protein | 1ow4 | ||||||||
| |||||||||
In molecular biology, the insect pheromone-binding family A10/OS-D is a family of proteins found in insects.
A class of small (14-20 Kd) water-soluble proteins, called odorant binding proteins (OBPs), first discovered in the insect sensillar lymph but also found in the mucus of vertebrates, is postulated to mediate the solubilisation of hydrophobic odorant molecules, and thereby to facilitate their transport to the receptor neurons. The product of a gene expressed in the olfactory system of Drosophila melanogaster (Fruit fly), OS-D, shares features common to vertebrate odorant-binding proteins, but has a primary structure unlike odorant-binding proteins.[1] OS-D derivatives have subsequently been found in chemosensory organs of phylogenetically distinct insects, including cockroaches, phasmids and moths, suggesting that OS-D-like proteins seem to be conserved in the insect phylum. OS-D and related proteins are members of the insect pheromone-binding family A10/OS-D.
References
Further reading
- Angeli S, Ceron F, Scaloni A, Monti M, Monteforti G, Minnocci A, et al. (1999). "Purification, structural characterization, cloning and immunocytochemical localization of chemoreception proteins from Schistocerca gregaria.". Eur J Biochem. 262 (3): 745–54. doi:10.1046/j.1432-1327.1999.00438.x. PMID 10411636.
This article incorporates text from the public domain Pfam and InterPro IPR005055