Mallotophenone

Mallotophenone
Chemical structure of mallotophenone
Names
IUPAC name
1-[3-[(3-acetyl-2,4-dihydroxy-6-methoxy-5-methylphenyl)methyl]-2,6-dihydroxy-4-methoxy-5-methylphenyl]ethanone
Identifiers
98569-63-2
3D model (Jmol) Interactive image
ChemSpider 155882
KEGG C10708
PubChem 179090
Properties
C21H24O8
Molar mass 404.41 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Mallotophenone is a dimeric phlorogucinol found in Mallotus oppositifolius or in Mallotus japonicus.

The bioassay-guided fractionation of an ethanol extract of the leaves and inflorescence of M. oppositifolius collected in Madagascar led to the isolation of the two new bioactive dimeric phloroglucinols mallotophenone, together with mallotojaponins B and C. These compounds show antiproliferative and antiplasmodial activities.[1]

References

  1. Harinantenaina, Liva; Bowman, Jessica D.; Brodie, Peggy J.; Slebodnick, Carla; Callmander, Martin W.; Rakotobe, Etienne; Randrianaivo, Richard; Rasamison, Vincent E.; Gorka, Alexander; Roepe, Paul D.; Cassera, Maria B.; Kingston, David G. I. (2013). "Antiproliferative and Antiplasmodial Dimeric Phloroglucinols fromMallotus oppositifoliusfrom the Madagascar Dry Forest(1)". Journal of Natural Products. 76 (3): 388–93. doi:10.1021/np300750q. PMC 3606680Freely accessible. PMID 23286240.
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