Mean residence time

The mean residence time (MRT) in pharmacokinetics is the average amount of time that a single molecule of drug stays in the body.^[1] It is defined as the sum of all the residence times (the amount of time that an individual molecule of drug stays in the body) divided by the number of molecules.^[1]

References

1 2 David B. Troy; Paul Beringer (2006). Remington: The Science and Practice of Pharmacy. Lippincott Williams & Wilkins. pp. 1181–. ISBN 978-0-7817-4673-1.

External links

Mean residence time (MRT): Understanding how long drug molecules stay in the body

Concepts in pharmacology

Pharmacokinetics	(L)ADME: (Liberation) Absorption Distribution Metabolism Excretion (Clearance) Loading dose Volume of distribution (Initial) Rate of infusion Compartment Bioequivalence Bioavailability Onset of action Biological half-life Mean residence time Plasma protein binding Therapeutic index (Median lethal dose, Effective dose)

Pharmacodynamics	Mechanism of action Toxicity (Neurotoxicology) Dose–response relationship (Efficacy, Potency) Antimicrobial pharmacodynamics: Minimum inhibitory concentration (Bacteriostatic) Minimum bactericidal concentration (Bactericide)

Agonism and antagonism	Agonist: Inverse agonist Irreversible agonist Partial agonist Superagonist Physiological agonist Antagonist: Competitive antagonist Irreversible antagonist Physiological antagonist Other: Binding Affinity Binding selectivity Functional selectivity

Other	Drug tolerance: Tachyphylaxis Drug resistance: Antibiotic resistance Multiple drug resistance

Drug discovery strategies	Classical pharmacology Reverse pharmacology

Related fields/subfields	Pharmacogenetics Pharmacogenomics Neuropsychopharmacology (Neuropharmacology, Psychopharmacology)

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Mean residence time

See also

References

External links