NAV2

NAV2
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
Aliases NAV2, HELAD1, POMFIL2, RAINB1, STEERIN2, UNC53H2, neuron navigator 2
External IDs MGI: 2183691 HomoloGene: 52330 GeneCards: NAV2
Genetically Related Diseases
obesity[1]
Orthologs
Species Human Mouse
Entrez

89797

78286

Ensembl

ENSG00000166833

ENSMUSG00000052512

UniProt

Q8IVL1

n/a

RefSeq (mRNA)

NM_001111018
NM_001111019
NM_001244963
NM_145117
NM_182964

NM_001111016
NM_175272

RefSeq (protein)

NP_001104488.1
NP_001104489.1
NP_001231892.1
NP_660093.2
NP_892009.3

n/a

Location (UCSC) Chr 11: 19.35 – 20.12 Mb Chr 7: 48.9 – 49.61 Mb
PubMed search [2] [3]
Wikidata
View/Edit HumanView/Edit Mouse

Neuron navigator 2 is a protein that in humans is encoded by the NAV2 gene.[4][5][6]

The vitamin A metabolite, all-trans retinoic acid (atRA), plays an important role in neuronal development, including neurite outgrowth. RAINB1 is an atRA-responsive gene.[6]

References

  1. "Diseases that are genetically associated with NAV2 view/edit references on wikidata".
  2. "Human PubMed Reference:".
  3. "Mouse PubMed Reference:".
  4. Maes T, Barcelo A, Buesa C (Jun 2002). "Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans". Genomics. 80 (1): 21–30. doi:10.1006/geno.2002.6799. PMID 12079279.
  5. Coy JF, Wiemann S, Bechmann I, Bachner D, Nitsch R, Kretz O, Christiansen H, Poustka A (Jun 2002). "Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms". Gene. 290 (1–2): 73–94. doi:10.1016/S0378-1119(02)00567-X. PMID 12062803.
  6. 1 2 "Entrez Gene: NAV2 neuron navigator 2".

Further reading


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