NRK (gene)

NRK

Identifiers

NRK, NESK, Nik related kinase

External IDs

MGI: 1351326 HomoloGene: 8442 GeneCards: NRK

Gene ontology
Molecular function	• transferase activity • nucleotide binding • protein kinase activity • ATP binding • kinase activity • signal transducer, downstream of receptor, with serine/threonine kinase activity • protein serine/threonine kinase activity
Cellular component	• cytoplasm
Biological process	• protein phosphorylation • activation of JNKK activity • regulation of spongiotrophoblast cell proliferation • parturition • phosphorylation • negative regulation of cell proliferation
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


203447


27206


ENSG00000123572


ENSMUSG00000052854


Q7Z2Y5


Q9R0G8

RefSeq (mRNA)


NM_198465


NM_013724

RefSeq (protein)


NP_940867.2


NP_038752.2

Location (UCSC)

Chr X: 105.82 – 105.96 Mb

Chr X: 138.91 – 139.01 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

Nik-related protein kinase is an enzyme that is encoded by the NRK gene in humans.^[3]

References

Further reading

Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Nakano K, Kanai-Azuma M, Kanai Y, et al. (2003). "Cofilin phosphorylation and actin polymerization by NRK/NESK, a member of the germinal center kinase family". Exp. Cell Res. 287 (2): 219–27. doi:10.1016/S0014-4827(03)00136-8. PMID 12837278.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

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