O-(2-Fluorethyl)-L-thyrosine

O-(2-Fluorethyl)-L-thyrosine
Clinical data

Routes of administration	intravenous
Identifiers
IUPAC name (2S)-2-Amino-3-[4-(2-fluoroethoxy)phenyl]propanoic acid
Synonyms	¹⁸F-FET; O-(2-(¹⁸F)fluoroethyl)-L-tyrosine, O-(2-fluoroethyl)tyrosine, L-(¹⁸F)FET^[1]
PubChem (CID)	54255856
UNII	3Y68K91A3M
Chemical and physical data
Formula	C₁₁H₁₄FNO₃
Molar mass	227.23 g/mol
3D model (Jmol)	Interactive image
SMILES C1=CC(=CC=C1CC(C(=O)O)N)OCCF
InChI InChI=1S/C11H14FNO3/c12-5-6-16-9-3-1-8(2-4-9)7-10(13)11(14)15/h1-4,10H,5-7,13H2,(H,14,15)/t10-/m0/s1 Key:QZZYPHBVOQMBAT-JTQLQIEISA-N

O-(2-Fluorethyl)-L-thyrosine or ¹⁸F-FET is an neuro-oncologic PET tracer.^[2]

References

↑ CID 54255856 from PubChem
↑ Galldiks, N.; Stoffels, G.; Filss, C.; Rapp, M.; Blau, T.; Tscherpel, C.; Ceccon, G.; Dunkl, V.; Weinzierl, M.; Stoffel, M.; Sabel, M.; Fink, G. R.; Shah, N. J.; Langen, K.-J. (2015). "The use of dynamic O-(2-18F-fluoroethyl)-L-tyrosine PET in the diagnosis of patients with progressive and recurrent glioma". Neuro-Oncology. doi:10.1093/neuonc/nov088.

Diabetes	Glucose Tolbutamide

Fat absorption	Vitamin A concentrates

Bile duct patency	Ceruletide Magnesium sulfate Sincalide Sorbitol

Liver functional capacity	Galactose Sulfobromophthalein

Gastric secretion	Betazole Caffeine and sodium benzoate Cation exchange resins Histamine phosphate Methylthioninium chloride Pentagastrin

Exocrine pancreatic function	Bentiromide Pancreozymin cholecystokinin Secretin

Pituitary function	cortisol Corticorelin Metyrapone GH Pralmorelin Sermorelin Somatorelin

Thyroid function	Protirelin Thyrotropin

Fertility disturbances	Gonadorelin

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