PLSCR2

PLSCR2

Identifiers

External IDs

HomoloGene: 124471 GeneCards: PLSCR2

Gene ontology
Molecular function	• phospholipid scramblase activity • calcium ion binding • metal ion binding
Cellular component	• integral component of membrane • plasma membrane • membrane • nucleus
Biological process	• phospholipid scrambling
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


57047


n/a


ENSG00000163746


n/a


Q9NRY7


n/a

RefSeq (mRNA)


NM_001199978 NM_001199979 NM_020359


n/a

RefSeq (protein)


NP_001186907.1 NP_001186908.1 NP_065092.1


n/a

Location (UCSC)

Chr 3: 146.39 – 146.5 Mb

n/a

PubMed search

^[1]

n/a

View/Edit Human

Phospholipid scramblase 2, also known as Ca²⁺-dependent phospholipid scramblase 2, is a protein that in humans is encoded by the PLSCR2 gene.^[2]^[3]

See also

scramblase

References

↑ "Human PubMed Reference:".
↑ "Entrez Gene: phospholipid scramblase 2".
↑ Wiedmer T, Zhou Q, Kwoh DY, Sims PJ (July 2000). "Identification of three new members of the phospholipid scramblase gene family". Biochim. Biophys. Acta. 1467 (1): 244–53. doi:10.1016/S0005-2736(00)00236-4. PMID 10930526.

Further reading

Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Sahu SK, Aradhyam GK, Gummadi SN (2009). "Calcium binding studies of peptides of human phospholipid scramblases 1 to 4 suggest that scramblases are new class of calcium binding proteins in the cell.". Biochim. Biophys. Acta. 1790 (10): 1274–81. doi:10.1016/j.bbagen.2009.06.008. PMID 19540310.
Yu A, McMaster CR, Byers DM, et al. (2003). "Stimulation of phosphatidylserine biosynthesis and facilitation of UV-induced apoptosis in Chinese hamster ovary cells overexpressing phospholipid scramblase 1.". J. Biol. Chem. 278 (11): 9706–14. doi:10.1074/jbc.M204614200. PMID 12509439.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

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