PPP1R14B

PPP1R14B

Identifiers

PPP1R14B, PHI-1, PLCB3N, PNG, SOM172, protein phosphatase 1 regulatory inhibitor subunit 14B

External IDs

MGI: 107682 HomoloGene: 7483 GeneCards: PPP1R14B

Gene ontology
Molecular function	• protein phosphatase inhibitor activity • protein serine/threonine phosphatase inhibitor activity
Cellular component	• cytoplasm
Biological process	• regulation of phosphorylation • regulation of protein dephosphorylation • negative regulation of catalytic activity • innate immune response
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


26472


18938


ENSG00000173457


ENSMUSG00000056612


Q96C90


Q62084

RefSeq (mRNA)


NM_138689


NM_008889

RefSeq (protein)


NP_619634.1


NP_032915.2

Location (UCSC)

Chr 11: 64.24 – 64.25 Mb

Chr 19: 6.98 – 6.98 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

Protein phosphatase 1 regulatory subunit 14B is an enzyme that in humans is encoded by the PPP1R14B gene.^[3]^[4]^[5]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Lagercrantz J, Carson E, Larsson C, Nordenskjold M, Weber G (Mar 1997). "Isolation and characterization of a novel gene close to the human phosphoinositide-specific phospholipase C beta 3 gene on chromosomal region 11q13". Genomics. 31 (3): 380–4. doi:10.1006/geno.1996.0063. PMID 8838322.
↑ Eto M, Karginov A, Brautigan DL (Jan 2000). "A novel phosphoprotein inhibitor of protein type-1 phosphatase holoenzymes". Biochemistry. 38 (51): 16952–7. doi:10.1021/bi992030o. PMID 10606530.
↑ "Entrez Gene: PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B".

Further reading

Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Tountas NA, Mandell JW, Everett AD, Brautigan DL (2005). "Juxtamembrane localization of the protein phosphatase-1 inhibitor protein PHI-1 in smooth muscle cells.". Histochem. Cell Biol. 121 (4): 343–50. doi:10.1007/s00418-004-0642-8. PMID 15083373.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Tountas NA, Brautigan DL (2005). "Migration and retraction of endothelial and epithelial cells require PHI-1, a specific protein-phosphatase-1 inhibitor protein.". J. Cell. Sci. 117 (Pt 24): 5905–12. doi:10.1242/jcs.01506. PMID 15522888.
Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer.". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.

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