PPP4R1

PPP4R1
Identifiers
Aliases PPP4R1, MEG1, PP4(Rmeg), PP4R1, protein phosphatase 4 regulatory subunit 1
External IDs MGI: 1917601 HomoloGene: 81737 GeneCards: PPP4R1
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

9989

70351

Ensembl

ENSG00000154845

ENSMUSG00000061950

UniProt

Q8TF05

Q8K2V1

RefSeq (mRNA)

NM_001042388
NM_005134

NM_001114131
NM_146081

RefSeq (protein)

NP_001035847.1
NP_005125.1

NP_001107603.1
NP_666193.2

Location (UCSC) Chr 18: 9.55 – 9.62 Mb Chr 17: 65.78 – 65.84 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Serine/threonine-protein phosphatase 4 regulatory subunit 1 is an enzyme that in humans is encoded by the PPP4R1 gene.[3][4]

Interactions

PPP4R1 has been shown to interact with PPP4C.[5][6][7]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Kloeker S, Wadzinski BE (Feb 1999). "Purification and identification of a novel subunit of protein serine/threonine phosphatase 4". The Journal of Biological Chemistry. 274 (9): 5339–47. doi:10.1074/jbc.274.9.5339. PMID 10026142.
  4. "Entrez Gene: PPP4R1 protein phosphatase 4, regulatory subunit 1".
  5. Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948Freely accessible. PMID 17353931.
  6. Chen GI, Tisayakorn S, Jorgensen C, D'Ambrosio LM, Goudreault M, Gingras AC (Oct 2008). "PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4". The Journal of Biological Chemistry. 283 (43): 29273–84. doi:10.1074/jbc.M803443200. PMC 2662017Freely accessible. PMID 18715871.
  7. Gingras AC, Caballero M, Zarske M, Sanchez A, Hazbun TR, Fields S, Sonenberg N, Hafen E, Raught B, Aebersold R (Nov 2005). "A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity". Molecular & Cellular Proteomics. 4 (11): 1725–40. doi:10.1074/mcp.M500231-MCP200. PMID 16085932.

Further reading

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