60S ribosomal protein L39

RPL39
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UG0, 4V6X, 5AJ0, 3J92, 4UJC, 3J7P, 4UJE, 3J7Q, 3J7R, 4D67, 4UJD, 4V5Z, 4D5Y, 3J7O
Identifiers
Aliases	RPL39, L39, RPL39P42, RPL39_23_1806, ribosomal protein L39
External IDs	MGI: 1914498 HomoloGene: 133571 GeneCards: RPL39
Gene ontology Molecular function • RNA binding • structural constituent of ribosome Cellular component • ribosome • cytosol • extracellular space • intracellular • intracellular ribonucleoprotein complex • cytosolic large ribosomal subunit Biological process • SRP-dependent cotranslational protein targeting to membrane • innate immune response in mucosa • antibacterial humoral response • viral transcription • defense response to Gram-positive bacterium • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay • translational initiation • translation • rRNA processing Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6170	67248
Ensembl	ENSG00000198918	ENSMUSG00000079641
UniProt	P62891	P62892
RefSeq (mRNA)	NM_001000	NM_026055
RefSeq (protein)	NP_000991.1	NP_080331.1
Location (UCSC)	Chr X: 119.79 – 119.79 Mb	Chr X: 37.08 – 37.09 Mb
PubMed search	[1]	[2]
Wikidata

60S ribosomal protein L39 is a protein that in humans is encoded by the RPL39 gene.^[3][4]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the S39E family of ribosomal proteins. It is located in the cytoplasm. In rat, the protein is the smallest, and one of the most basic, proteins of the ribosome. This gene is co-transcribed with the U69 small nucleolar RNA gene, which is located in its second intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[4]

References

Further reading