SFRS2IP

SCAF11

Identifiers

SCAF11, CASP11, SFRS2IP, SIP1, SRRP129, SRSF2IP, SR-related CTD associated factor 11

External IDs

MGI: 1919443 HomoloGene: 37957 GeneCards: SCAF11

Gene ontology
Molecular function	• zinc ion binding • poly(A) RNA binding • protein binding • metal ion binding
Cellular component	• nucleolus • nucleus • nucleoplasm
Biological process	• RNA splicing, via transesterification reactions • mRNA processing • spliceosomal complex assembly • RNA splicing
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


9169


72193

Ensembl


ENSG00000139218


ENSMUSG00000033228

UniProt


Q99590


n/a

RefSeq (mRNA)


NM_004719


NM_028148

RefSeq (protein)


NP_004710.2


n/a

Location (UCSC)

Chr 12: 45.92 – 45.99 Mb

Chr 15: 96.41 – 96.46 Mb

PubMed search

^[1]

^[2]

Wikidata

View/Edit Human

View/Edit Mouse

SFRS2-interacting protein is a protein that in humans is encoded by the SFRS2IP gene.^[3]^[4]^[5]

Interactions

SFRS2IP has been shown to interact with U2AF2.^[4]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Tanner S, Stagljar I, Georgiev O, Schaffner W, Bourquin JP (Aug 1997). "A novel SR-related protein specifically interacts with the carboxy-terminal domain (CTD) of RNA polymerase II through a conserved interaction domain". Biol Chem. 378 (6): 565–71. PMID 9224939.
1 2 Zhang WJ, Wu JY (Feb 1998). "Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing". Mol Cell Biol. 18 (2): 676–84. PMC 108778. PMID 9447963.
↑ "Entrez Gene: SFRS2IP splicing factor, arginine/serine-rich 2, interacting protein".

Gui JF, Lane WS, Fu XD (1994). "A serine kinase regulates intracellular localization of splicing factors in the cell cycle.". Nature. 369 (6482): 678–82. doi:10.1038/369678a0. PMID 8208298.
van de Craen M, de Jonghe C, van den Brande I, et al. (1999). "Identification of caspases that cleave presenilin-1 and presenilin-2. Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases.". FEBS Lett. 445 (1): 149–54. doi:10.1016/S0014-5793(99)00108-8. PMID 10069390.
Scanlan MJ, Gordan JD, Williamson B, et al. (1999). "Antigens recognized by autologous antibody in patients with renal-cell carcinoma.". Int. J. Cancer. 83 (4): 456–64. doi:10.1002/(SICI)1097-0215(19991112)83:4<456::AID-IJC4>3.0.CO;2-5. PMID 10508479.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.

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SFRS2IP

Interactions

References

Further reading