SLC25A19
Mitochondrial thiamine pyrophosphate carrier is a protein that in humans is encoded by the SLC25A19 gene.[3][4][5]
See also
References
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- ↑ Iacobazzi V, Ventura M, Fiermonte G, Prezioso G, Rocchi M, Palmieri F (Jul 2001). "Genomic organization and mapping of the gene (SLC25A19) encoding the human mitochondrial deoxynucleotide carrier (DNC)". Cytogenet Cell Genet. 93 (1–2): 40–2. doi:10.1159/000056945. PMID 11474176.
- ↑ Dolce V, Fiermonte G, Runswick MJ, Palmieri F, Walker JE (Mar 2001). "The human mitochondrial deoxynucleotide carrier and its role in the toxicity of nucleoside antivirals". Proc Natl Acad Sci U S A. 98 (5): 2284–8. doi:10.1073/pnas.031430998. PMC 30130
. PMID 11226231. - ↑ "Entrez Gene: SLC25A19 solute carrier family 25 (mitochondrial deoxynucleotide carrier), member 19".
Further reading
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Rosenberg MJ, Agarwala R, Bouffard G, et al. (2002). "Mutant deoxynucleotide carrier is associated with congenital microcephaly". Nat. Genet. 32 (1): 175–9. doi:10.1038/ng948. PMID 12185364.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Carrisi C, Antonucci D, et al. (2013). "Transport of platinum bonded nucleotides into proteoliposomes, mediated by Drosophila melanogaster thiamine pyrophosphate carrier protein (DmTpc1).". j.jinorgbio. 130: 1172. doi:10.1016/j.jinorgbio.2013.09.012. PMID 24148759.
- Lam W, Chen C, Ruan S, et al. (2005). "Expression of deoxynucleotide carrier is not associated with the mitochondrial DNA depletion caused by anti-HIV dideoxynucleoside analogs and mitochondrial dNTP uptake". Mol. Pharmacol. 67 (2): 408–16. doi:10.1124/mol.104.007120. PMID 15539640.
- Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
- Lindhurst MJ, Fiermonte G, Song S, et al. (2006). "Knockout of Slc25a19 causes mitochondrial thiamine pyrophosphate depletion, embryonic lethality, CNS malformations, and anemia". Proc. Natl. Acad. Sci. U.S.A. 103 (43): 15927–32. doi:10.1073/pnas.0607661103. PMC 1595310. PMID 17035501.
- Iacopetta D, Carrisi C, et al. (2010). "The biochemical properties of the mitochondrial thiamine pyrophosphate carrier from Drosophila melanogaster.". Febs J. 277: 1172. doi:10.1111/j.1742-4658.2009.07550.x. PMID 20121944.
External links
|
|---|
|
| By group |
|---|
| | SLC1–10 |
|---|
| | (1): | |
|---|
| | (2): | |
|---|
| | (3): | |
|---|
| | (4): | |
|---|
| | (5): | |
|---|
| | (6): | |
|---|
| | (7): | |
|---|
| | (8): | |
|---|
| | (9): | |
|---|
| | (10): | |
|---|
|
| | | SLC11–20 |
|---|
| | (11): |
- proton coupled metal ion transporter
|
|---|
| | (12): | |
|---|
| | (13): |
- human Na+-sulfate/carboxylate cotransporter
|
|---|
| | (14): | |
|---|
| | (15): |
- proton oligopeptide cotransporter
|
|---|
| | (16): |
- monocarboxylate transporter
|
|---|
| | (17): | |
|---|
| | (18): | |
|---|
| | (19): | |
|---|
| | (20): | |
|---|
|
| | | SLC21–30 |
|---|
| | (21): | |
|---|
| | (22): | |
|---|
| | (23): |
- Na+-dependent ascorbic acid transporter
|
|---|
| | (24): | |
|---|
| | (25): | |
|---|
| | (26): |
- multifunctional anion exchanger
|
|---|
| | (27): | |
|---|
| | (28): |
- Na+-coupled nucleoside transport (SLC28A1
|
|---|
| | (29): |
- facilitative nucleoside transporter
|
|---|
| | (30): | |
|---|
|
| | | SLC31–40 |
|---|
| | (31): | |
|---|
| | (32): | |
|---|
| | (33): | |
|---|
| | (34): |
- type II Na+-phosphate cotransporter
|
|---|
| | (35): |
- nucleoside-sugar transporter
-
-
-
-
- SLC35E1
- SLC35E2
- SLC35E3
- SLC35E4
|
|---|
| | (36): |
- proton-coupled amino-acid transporter
|
|---|
| | (37): |
- sugar-phosphate/phosphate exchanger
|
|---|
| | (38): |
- System A & N, sodium-coupled neutral amino-acid transporter
|
|---|
| | (39): | |
|---|
| | (40): |
- basolateral iron transporter
|
|---|
|
| | | SLC41–48 |
|---|
| | (41): | |
|---|
| | (42): | |
|---|
| | (43): |
- Na+-independent, system-L like amino-acid transporter
|
|---|
| | (44): | |
|---|
| | (45): |
- Putative sugar transporter
|
|---|
| | (46): | |
|---|
| | (47): | |
|---|
| | (48): | |
|---|
|
| | |
|
|
|
|
|
see also solute carrier disorders |