SMCR7L

MIEF1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4NXT, 4NXU, 4NXV, 4NXW, 4NXX
Identifiers
Aliases	MIEF1, HSU79252, MID51, SMCR7L, dJ1104E15.3, mitochondrial elongation factor 1
External IDs	MGI: 2146020 HomoloGene: 10374 GeneCards: MIEF1
Gene ontology Molecular function • nucleotide binding • ADP binding • protein binding • GDP binding • identical protein binding Cellular component • integral component of membrane • mitochondrial outer membrane • peroxisome • membrane • mitochondrion Biological process • mitochondrial fusion • positive regulation of mitochondrial fission • mitochondrial fission • positive regulation of protein targeting to membrane Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	54471	239555
Ensembl	ENSG00000100335	ENSMUSG00000022412
UniProt	Q9NQG6	Q8BGV8
RefSeq (mRNA)	NM_001304564 NM_013298 NM_019008	NM_178719
RefSeq (protein)	NP_001291493.1 NP_061881.2	NP_848834.2
Location (UCSC)	Chr 22: 39.5 – 39.52 Mb	Chr 15: 80.23 – 80.25 Mb
PubMed search	[1]	[2]
Wikidata

Mitochondrial dynamic protein MID51 (MID51) also known as mitochondrial elongation factor 1 (MIEF1) or Smith-Magenis syndrome chromosome region candidate gene 7 protein-like (SMCR7L) is a protein that in humans is encoded by the SMCR7L gene.^[3][4][5]

Function

The SMCR7L gene codes for a protein that has been called MiD51/MIEF1 and shown to regulate mitochondrial fission by interacting with the proteins Drp1 and FIS1.^[6]

References

Further reading