Spleen transplantation

Spleen transplantation
Intervention
ICD-9-CM	41.94

Spleen transplantation is the transfer of spleen or spleen fragments from one individual to another. It is under research for induction of immunological tolerance for other transplanted organs. Success has been achieved in rodent models. Recently, evidence has been obtained for a tolerogenic effect of a spleen transplant in miniature swine (Frank JMF Dor, PhD thesis). Also, the spleen harbors primitive hematopoietic progenitor cells. Spleen transplantation surgery has been performed on humans with mixed results.^[1]^[2]

References

↑ Wu; et al. (January 2011). "Graft-versus-host disease after intestinal and multivisceral transplantation.". Transplantation. 91 (2): 219–224. doi:10.1097/tp.0b013e3181ff86ec. PMID 21076376.
↑ Deierhoi; et al. (April 1986). "Lethal graft-versus-host disease in a recipient of a pancreas-spleen transplant.". Transplantation. 41 (4): 544–546. doi:10.1097/00007890-198604000-00028. PMID 3515658.

Organ transplantation

Types

Organs and tissues

Medical grafting

Organ donation

Complications

Organizations

Countries

People

Heart	Christiaan Barnard James D. Hardy Adrian Kantrowitz Richard Lower Norman Shumway

Kidney	J. Hartwell Harrison John P. Merrill Joseph Murray Michael Woodruff

Liver	Fikri Alican James D. Hardy Thomas Starzl

Lung	Fikri Alican Joel D. Cooper Vladimir Demikhov James D. Hardy

Penis	André van der Merwe

Other	Alexis Carrel Jean-Michel Dubernard Donna Mansell Bruce Reitz

List of organ transplant donors and recipients

Related topics

Operations/surgeries and other procedures of the blood and lymphatic system (ICD-9-CM V3 40–41, ICD-10-PCS 07)

Bone marrow	Stem cell transplantation/Hematopoietic stem cell transplantation

Thymus	Thymectomy Thymus transplantation

Spleen	Splenectomy Spleen transplantation

Lymph nodes	Lymphadenectomy Neck dissection Retroperitoneal lymph node dissection Lymph node biopsy

Tonsils	see Template:Procedures on the mouth and pharynx

Imaging	Lymphogram

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