TRIM62

TRIM62, also called DEAR1 (for ductal epithelium–associated RING chromosome 1),[1] is a protein in the tripartite motif family. In human it is encoded by the gene TRIM62.[2] TRIM62 is involved in the morphogenesis of the mammary gland, and loss of TRIM62 gene expression in breast is associated with a higher risk of recurrence in early-onset breast cancer.[1]

References

  1. 1 2 Lott ST, Chen N, Chandler DS, Yang Q, Wang L, et al. (2009). Minna JD, ed. "DEAR1 Is a Dominant Regulator of Acinar Morphogenesis and an Independent Predictor of Local Recurrence-Free Survival in Early-Onset Breast Cancer". PLoS Medicine. 6 (5): e1000068. doi:10.1371/journal.pmed.1000068. PMC 2673042Freely accessible. PMID 19536326.
  2. ↑ "TRIM62 tripartite motif-containing 62 [ Homo sapiens ]". Entrez Gene. Retrieved 1 Jun 2009.
This article is issued from Wikipedia - version of the 9/2/2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.