Thiouric acid
 | |
| Names | |
|---|---|
| IUPAC name
6-Thioxo-7,9-dihydro-1H-purine-2,8(3H,6H)-dione | |
| Other names
6-Thiouric acid | |
| Identifiers | |
| 2002-60-0 | |
| 3D model (Jmol) | Interactive image |
| ChEBI | CHEBI:80608 |
| ChemSpider | 2297400 |
| KEGG | C16613 |
| PubChem | 3032417 |
| |
| |
| Properties | |
| C5H4N4O2S | |
| Molar mass | 184.17 g·mol−1 |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Thiouric acid, more accurately called 6-thiouric acid, is a main inactive metabolite of the immunosuppressive drugs azathioprine, mercaptopurine and tioguanine.[1][2]
References
- ↑ Mutschler, Ernst; Schäfer-Korting, Monika (2001). Arzneimittelwirkungen (in German) (8 ed.). Stuttgart: Wissenschaftliche Verlagsgesellschaft. pp. 107, 936. ISBN 3-8047-1763-2.
- ↑ Ansari, A; Aslam, Z; De Sica, A; Smith, M; Gilshenan, K; Fairbanks, L; Marinaki, A; Sanderson, J; Duley, J (2008). "Influence of xanthine oxidase on thiopurine metabolism in Crohn's disease". Alimentary Pharmacology & Therapeutics. 28 (6): 749–57. doi:10.1111/j.1365-2036.2008.03768.x. PMID 18557988.
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