Tramazoline

Tramazoline
Clinical data

AHFS/Drugs.com	International Drug Names
ATC code	R01AA09 (WHO)
Identifiers
IUPAC name N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine
CAS Number	1082-57-1^N
PubChem (CID)	5524
ChemSpider	5323^N
UNII	SLE31693IV^Y
KEGG	D08624^N
ChEMBL	CHEMBL32573^N
ECHA InfoCard	100.012.823
Chemical and physical data
Formula	C₁₃H₁₇N₃
Molar mass	215.294 g/mol
^NY (what is this?) (verify)

Tramazoline is a chemical that is used in the form of tramazoline hydrochloride in nasal decongestant preparations.^[1] It is an α-adrenergic receptor agonist that inhibits secretion of nasal mucus.

It causes hypertension.^[2]

Product names

Australia

Spray-Tish^[3]
Rhinaspray

Austria

Rhinorix

Belgium

Rhinospray

Czech Republic

Muconasal Plus

Germany

Biciron
Ellatun
Rhinospray

Italy

Rinogutt

Romania

Muconasal Plus (older)
Muconasal (newer)

Russia

Adrianol (tramazoline + phenylephrine)
Lasolvan Rhino

Spain

Rhinospray

Slovakia

Muconasal Plus

Ukraine

Lasorin

References

↑ Boehringer Ingelheim. "Spray-Tish Consumer Information". Consumer Medicines Information. MyDr.com.au. Retrieved 16 April 2011.
↑ Peng N, Meng QC, King K, Oparil S, Wyss JM (April 1995). "Acute hypertension increases norepinephrine release in the anterior hypothalamic area". Hypertension. 25 (4 Pt 2): 828–33. doi:10.1161/01.hyp.25.4.828. PMID 7721439.
↑ "Spray-Tish". Consumer Information. Retrieved 16 April 2011.

Decongestants and other nasal preparations (R01)

Topical

Sympathomimetics, plain	Cyclopentamine Ephedrine Epinephrine Fenoxazoline Levomethamphetamine Metizoline Naphazoline Oxymetazoline Phenylephrine Propylhexedrine Tetryzoline Tramazoline Tuaminoheptane Tymazoline Xylometazoline

Antiallergic agents, excluding corticosteroids	Spaglumic acid histamine antagonists (Levocabastine Antazoline Thonzylamine) mast cell stabilizer (some are also antihistamines) (Cromoglicic acid Nedocromil Azelastine Olopatadine Lodoxamide)

Corticosteroids	Beclometasone dipropionate Betamethasone Budesonide Ciclesonide Dexamethasone Flunisolide Fluticasone Mometasone furoate Prednisolone Tixocortol Triamcinolone

Other nasal preparations	Cafaminol Calcium hexamine thiocyanate Eucalyptus oil Framycetin Hexamidine Hyaluronan Ipratropium bromide Mupirocin Retinol Ritiometan Saline water

Systemic use:
Sympathomimetics

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