Trehalose dimycolate
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| Identifiers | |
|---|---|
61512-20-7  | |
| 3D model (Jmol) | Interactive image |
| PubChem | 451713 |
| |
| Properties | |
| C130H250O15 | |
| Molar mass | 2,053.42 g·mol−1 |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
verify (what is  ?) | |
| Infobox references | |
Trehalose dimycolate is a molecule produced by Mycobacterium tuberculosis and other mycobacteria. Antimycobacterial drug SQ109 is thought to inhibit TDM production levels and in this way disrupts its cell wall assembly. [1]
References
- ↑ TAHLAN, K., R. WILSON, D. B. KASTRINSKY, K. ARORA, V. NAIR, E. FISCHER, S. W. BARNES, J. R. WALKER, D. ALLAND, C. E. BARRY a H. I. BOSHOFF. SQ109 Targets MmpL3, a Membrane Transporter of Trehalose Monomycolate Involved in Mycolic Acid Donation to the Cell Wall Core of Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 2012-03-16, vol. 56, issue 4, s. 1797-1809. DOI: 10.1128/AAC.05708-11. http://aac.asm.org/cgi/doi/10.1128/AAC.05708-11
See also
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