Tripamide
Clinical data | |
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AHFS/Drugs.com | International Drug Names |
Routes of administration | Oral |
ATC code | none |
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Identifiers | |
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CAS Number | 73803-48-2 |
PubChem (CID) | 636401 |
UNII | G36A0E9CVT |
ChEMBL | CHEMBL2104484 |
Chemical and physical data | |
Formula | C16H20ClN3O3S |
Molar mass | 369.86 |
3D model (Jmol) | Interactive image |
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Tripamide (INN) is a diuretic.
Synthesis
Preparation starts by exhaustive reduction of the Diels-Alder adduct from cyclopentadiene and maleimide (1). Nitrosation of the product (2), followed by reduction of the nitroso group of 3, gives the corresponding hydrazine (4). Acylation with acid chloride 5 gives tripamide (6).
References
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