TwoAYGGAY RNA motif

TwoAYGGAY RNA motif

Consensus secondary structure of TwoAYGGAY RNAs
Identifiers
Symbol TwoAYGGAY
Rfam RF01731
Other data
RNA type Cis-regulatory element
Domain(s) Bacteria

The TwoAYGGAY RNA motif is a conserved RNA structure identified by bioinformatics.[1] Its name refers to the conserved AYGGAY nucleotide sequence (Y refers to either an A or G nucleotide) found in the motif's two terminal loops (see diagram). The RNAs are found in sequences derived from DNA extracted from uncultivated bacteria present in the human gut, as well as some bacteria in the classes Clostridia and Gammaproteobacteria.

References

  1. Weinberg Z, Wang JX, Bogue J, et al. (March 2010). "Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea and their metagenomes". Genome Biol. 11 (3): R31. doi:10.1186/gb-2010-11-3-r31. PMC 2864571Freely accessible. PMID 20230605.
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