Tyropanoic acid

Tyropanoic acid
Ball-and-stick model of the tyropanoic acid molecule
Names
IUPAC name
2-[(3-butanamido-2,4,6-triiodophenyl)methyl]butanoic acid
Other names
2-[[2,4,6-triiodo-3-(1-oxobutylamino)phenyl]methyl]butanoic acid
Identifiers
27293-82-9 YesY
3D model (Jmol) Interactive image
ChEMBL ChEMBL1201261 N
ECHA InfoCard 100.043.976
PubChem 5611
Properties
C15H18I3NO3
Molar mass 641.02 g/mol
Pharmacology
V08AC09 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Tyropanoic acid and its salt sodium tyropanoate are radiocontrast agents used in cholecystography (X-ray diagnosis of gallstones). Trade names include Bilopaque, Lumopaque, Tyropaque, and Bilopac.[1] The molecule contains three heavy iodine atoms which obstruct X-rays in the same way as the calcium in bones to produce a visible image. After injection it is rapidly excreted into the bile.[2]

References

  1. "PubChem CID 5611".
  2. "Inhibition of hepatic binding of thyroxine by cholecystographic agents". J. Clin. Invest. 65 (5): 1032–40. May 1980. doi:10.1172/JCI109755. PMC 371433Freely accessible. PMID 7364937.


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