UPP1

UPP1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases UPP1, UDRPASE, UP, UPASE, UPP, uridine phosphorylase 1
External IDs MGI: 1097668 HomoloGene: 2524 GeneCards: UPP1
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

7378

22271

Ensembl

ENSG00000183696

ENSMUSG00000020407

UniProt

Q16831

P52624

RefSeq (mRNA)

NM_001159401
NM_001159402
NM_009477

RefSeq (protein)

NP_001274355.1
NP_001274357.1
NP_001274358.1
NP_001274359.1
NP_003355.1

NP_001152873.1
NP_001152874.1
NP_033503.2

Location (UCSC) Chr 7: 48.09 – 48.11 Mb Chr 11: 9.12 – 9.14 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Uridine phosphorylase 1 is an enzyme that in humans is encoded by the UPP1 gene.[3][4][5]

Interactions

UPP1 has been shown to interact with Vimentin.[6]

Interactive pathway map

Click on genes, proteins and metabolites below to link to respective articles. [§ 1]

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FluoropyrimidineActivity_WP1601 go to article go to article go to article go to pathway article go to pathway article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to PubChem Compound go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to pathway article go to pathway article go to article go to article go to article go to article go to article go to WikiPathways go to article go to article go to article go to article go to article go to article go to article go to article go to article

|{{{bSize}}}px|alt=Fluorouracil (5-FU) Activity edit]]

Fluorouracil (5-FU) Activity edit

  1. The interactive pathway map can be edited at WikiPathways: "FluoropyrimidineActivity_WP1601".

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Denney RM, Nichols EA, Ruddle FH (September 1979). "Assignment of a gene for uridine phosphorylase to chromosome 7". Cytogenet Cell Genet. 22 (1–6): 195–9. doi:10.1159/000130934. PMID 752472.
  4. Kanzaki A, Takebayashi Y, Bando H, Eliason JF, Watanabe Si S, Miyashita H, Fukumoto M, Toi M, Uchida T (January 2002). "Expression of uridine and thymidine phosphorylase genes in human breast carcinoma". Int J Cancer. 97 (5): 631–5. doi:10.1002/ijc.10105. PMID 11807789.
  5. "Entrez Gene: UPP1 uridine phosphorylase 1".
  6. Russell, R L; Cao D; Zhang D; Handschumacher R E; Pizzorno G (April 2001). "Uridine phosphorylase association with vimentin. Intracellular distribution and localization". J. Biol. Chem. United States. 276 (16): 13302–7. doi:10.1074/jbc.M008512200. ISSN 0021-9258. PMID 11278417.

Further reading


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