1-Methyltryptophan

1-Methyltryptophan
Names
IUPAC name
2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid
Other names
1-Methyl-DL-tryptophan; DL-1-Methyltryptophan; ARBRIN
Identifiers
26988-72-7 (D/L) N
21339-55-9 (L) YesY
3D model (Jmol) Interactive image
ChEMBL ChEMBL504816 N
ChEMBL514172 YesY
ChemSpider 88584 YesY
ECHA InfoCard 100.043.765
4694
PubChem 98112
Properties
C12H14N2O2
Molar mass 218.26 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

1-Methyltryptophan is a competitive inhibitor of indoleamine 2,3-dioxygenase (IDO or INDO EC 1.13.11.52).[1]

References

  1. Cady, SG; Sono, M (1991). "1-Methyl-DL-tryptophan, beta-(3-benzofuranyl)-DL-alanine (the oxygen analog of tryptophan), and beta-3-benzo(b)thienyl-DL-alanine (the sulfur analog of tryptophan) are competitive inhibitors for indoleamine 2,3-dioxygenase". Archives of Biochemistry and Biophysics. 291 (2): 326–33. doi:10.1016/0003-9861(91)90142-6. PMID 1952947.


This article is issued from Wikipedia - version of the 2/13/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.