EA-3167
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| CAS Number |
26758-53-2  Y |
| PubChem (CID) | 33597 |
| ChemSpider | 30995 |
| ChEMBL | CHEMBL13050 |
| Chemical and physical data | |
| Formula | C20H29NO3 |
| Molar mass | 329.433 g/mol |
| 3D model (Jmol) | Interactive image |
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EA-3167 is a potent and long-lasting anticholinergic deliriant drug, related to the chemical warfare agent 3-Quinuclidinyl benzilate (QNB). It was developed under contract to Edgewood Arsenal during the 1960s as part of the US military chemical weapons program, in an attempt to develop non-lethal incapacitating agents. EA-3167 has identical effects to QNB, but is even more potent and longer-lasting, with an effective dose when administered by injection of as little as 2.5μg/kg (i.e. 0.2 milligrams for an 80kg person), and a duration of 120-240 hours (5-10 days).[1][2] However unlike QNB, EA-3167 was never weaponized or manufactured in bulk.
See also
- Edgewood Arsenal human experiments
- N-methyl-3-piperidyl benzilate
- N-ethyl-3-piperidyl benzilate
- 3-Quinuclidinyl benzilate
- Ditran
References
- ↑ Wills H (1982). "Appendix I: Digest Report -- Anticholinergic Chemicals". In National Research Council (U.S.). Committee on Toxicology. Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents. 1. Washington, D.C.: National Academies Press. pp. 195–196. OCLC 35472774.
- ↑ Ketchum JS (2006). Chemical Warfare Secrets Almost Forgotton. A Personal Story of Medical Testing of Army Volunteers with Incapacitating Chemical Agents During the Cold War. ChemBooks. ISBN 978-1-4243-0080-8.
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