LRRFIP1

LRRFIP1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases LRRFIP1, FLAP-1, FLAP1, FLIIAP1, GCF-2, GCF2, HUFI-1, TRIP, leucine rich repeat (in FLII) interacting protein 1, LRR binding FLII interacting protein 1
External IDs MGI: 1342770 HomoloGene: 48301 GeneCards: LRRFIP1
RNA expression pattern




More reference expression data
Orthologs
Species Human Mouse
Entrez

9208

16978

Ensembl

ENSG00000124831

ENSMUSG00000026305

UniProt

Q32MZ4

Q3UZ39

RefSeq (mRNA)

NM_001137550
NM_001137551
NM_001137552
NM_001137553
NM_004735

NM_001111311
NM_001111312
NM_008515
NM_001310732

RefSeq (protein)

NP_001131022.1
NP_001131024.1
NP_001131025.1
NP_004726.2

NP_001104781.1
NP_001104782.1
NP_032541.1

Location (UCSC) Chr 2: 237.63 – 237.81 Mb Chr 1: 91 – 91.13 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Leucine-rich repeat flightless-interacting protein 1 is a protein that in humans is encoded by the LRRFIP1 gene.[3][4][5][6]

Interactions

LRRFIP1 has been shown to interact with FLII.[4][7]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Reed AL, Yamazaki H, Kaufman JD, Rubinstein Y, Murphy B, Johnson AC (Sep 1998). "Molecular cloning and characterization of a transcription regulator with homology to GC-binding factor". J Biol Chem. 273 (34): 21594–602. doi:10.1074/jbc.273.34.21594. PMID 9705290.
  4. 1 2 Liu YT, Yin HL (May 1998). "Identification of the binding partners for flightless I, A novel protein bridging the leucine-rich repeat and the gelsolin superfamilies". J Biol Chem. 273 (14): 7920–7. doi:10.1074/jbc.273.14.7920. PMID 9525888.
  5. Suriano AR, Sanford AN, Kim N, Oh M, Kennedy S, Henderson MJ, Dietzmann K, Sullivan KE (Oct 2005). "GCF2/LRRFIP1 represses tumor necrosis factor alpha expression". Mol Cell Biol. 25 (20): 9073–81. doi:10.1128/MCB.25.20.9073-9081.2005. PMC 1265793Freely accessible. PMID 16199883.
  6. "Entrez Gene: LRRFIP1 leucine rich repeat (in FLII) interacting protein 1".
  7. Fong KS, de Couet HG (Jun 1999). "Novel proteins interacting with the leucine-rich repeat domain of human flightless-I identified by the yeast two-hybrid system". Genomics. 58 (2): 146–57. doi:10.1006/geno.1999.5817. PMID 10366446.

Further reading


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