PROUD (clinical trial)

PROUD (a backronym for "Pre-exposure Option for reducing HIV in the UK: immediate or Deferred") was an open-label randomised clinical trial of pre-exposure prophylaxis (PrEP) by the MRC Clinical Trials Unit at University College London. It sought to evaluate the effectiveness of PrEP at preventing the spread of HIV in sexually active gay men in a non-controlled real-world environment. The study recruited participants at several different locations: Brighton, Birmingham, York, Manchester, Sheffield, and eight locations in London.[1]

The trial reported PrEP to have an 86% effectiveness in preventing HIV infection.[2][1][3]

References

  1. 1 2 Cairns, Gus (24 February 2015). "Pre-exposure prophylaxis (PrEP) stops 86% of HIV infections in PROUD study". Aidsmap. Retrieved 2016-08-02.
  2. ↑ McCormick, Joseph Patrick (24 February 2015). "PROUD study finds PrEP reduces risk of HIV infection by 86%". Pink News. Retrieved 2016-08-02.
  3. ↑ Dolling, David I.; Desai, Monica; McOwan, Alan; Gilson, Richard; Clarke, Amanda; Fisher, Martin; Schembri, Gabriel; Sullivan, Ann K.; Mackie, Nicola (2016-01-01). "An analysis of baseline data from the PROUD study: an open-label randomised trial of pre-exposure prophylaxis". Trials. 17: 163. doi:10.1186/s13063-016-1286-4. ISSN 1745-6215. PMC 4806447Freely accessible. PMID 27013513.

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