Policresulen

Policresulen
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration
topical
ATC code D08AE02 (WHO) G01AX03 (WHO) QG51AD02 (WHO)
Identifiers
CAS Number 101418-00-2 N
PubChem (CID) 3050404
ChemSpider none
UNII 6I19M5GB0G N
Chemical and physical data
Formula (C9H8O4S)n
Molar mass variable
 NYesY (what is this?)  (verify)

Policresulen is a topical haemostatic and antiseptic. It is indicated for common anal disorders, such as hemorrhoids, and for gynecological infections. In some countries it is marketed under the trade name Albothyl or Polilen (Taiwan) or Faktu (combination with Cinchocaine).

    Medical Uses

    Policresulen is often used for gynecological infections. In some countries, it is also used to treat canker sore. Although there is an immense pain followed by the application on canker sore, it is considered as a very effective treatment.

    Mechanism of Action

    As one can see from the chain of Policresulen, the molecule is negatively charged, making it acidic. In fact, its pKa is less than 0, yet it considered weak acid. The mechanism of action is that normal cells are negatively charged, therefore repelling each other. However, wounded part is positively charged, causing the Policresulen to be attracted. Policresulen basically makes a slight chemical burn on the wounded area, thus killing the bacteria and making it antiseptic.



    This article is issued from Wikipedia - version of the 9/15/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.