Scutellarin

Scutellarin
Names
Other names
Breviscapine; Breviscapin; Scutellarein-7-glucuronide; Scutellarein-7beta-D-glucuronide; Scutellarein-7beta-D-glucuronoside; Scutellarein-7-O-beta-D-glucuronide; 7-(β-D-glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Identifiers
27740-01-8 YesY
3D model (Jmol) Interactive image
ChEBI CHEBI:61278 N
ChEMBL ChEMBL487805 N
ChemSpider 161366 N
PubChem 185617
UNII 16IGP0ML9A N
Properties
C21H18O12
Molar mass 462.36 g/mol
Hazards
Lethal dose or concentration (LD, LC):
1314 mg/kg (mouse, intravenous) [1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Scutellarin is a flavone, a type of phenolic chemical compound. It can be found in Scutellaria barbata and S. lateriflora. The determination of the structure of scutellarin took Guido Goldschmiedt many years: after the first publication on that topic in 1901, only in 1910 he managed to obtain enough starting material for more detailed studies.

Scutellarin has been shown to induce apoptosis of ovarian and breast tumor cells in vitro.

References

  1. Zhongcaoyao (1983): Chinese Traditional and Herbal Medicine. Bd. 14, S. 33.
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