Tiazofurin
Clinical data | |
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ATC code | L01XX18 (WHO) |
Identifiers | |
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Synonyms | 2-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide |
CAS Number | 60084-10-8 |
PubChem (CID) | 457954 |
ChemSpider | 403014 |
UNII | ULJ82834RE |
ChEMBL | CHEMBL108358 |
Chemical and physical data | |
Formula | C9H12N2O5S |
Molar mass | 260.268 g/mol |
3D model (Jmol) | Interactive image |
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Tiazofurin is an inhibitor of IMP dehydrogenase. Tiazofurin and its analogues are under investigation for potential use in the treatment of cancer.[1]
References
- ↑ Popsavin M, Torović L, Svircev M, et al. (2006). "Synthesis and antiproliferative activity of two new tiazofurin analogues with 2'-amido functionalities". Bioorg. Med. Chem. Lett. 16 (10): 2773–6. doi:10.1016/j.bmcl.2006.02.001. PMID 16495053.
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